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Patients may interrupt treatment due to side effects, supply shortages, financial constraints, or medical procedures

Of the three aforementioned chemokines (CXCL10/IP-10, CCL2/MCP-1 and CXCL9), only one (MCP-1) was evaluated in terms of response to Aloe vera , and only by two studies (179, 180)

Searches also included websites of international and national societies and parent groups for inborn errors

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