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GSDMD, the pyroptosis executioner protein, forms plasma membrane pores via its N-terminal domain, causing cell death and releasing pro-inflammatory factors (IL-1, IL-18, HMGB1) that activate neighboring glial cells and recruit peripheral immune cells, amplifying neuroinflammatory feedback loops [49]

10.5662/wjm.v13.i3.29 98 NaderA

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[DOI] [PubMed] [Google Scholar] 1080.Westerbacka J., Cornr A., Kannisto K., Kolak M., Makkonen J., Korsheninnikova E., Nyman T., Hamsten A., Fisher R.M., Yki-Jrvinen H

Density Functional Thermochemistry III: The Role of Exact Exchange