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FIGURE 4 The previously documented constituents demonstrate multi-target efficacy against VEGF-driven tumor angiogenesis: fucoidan exhibits pan-inhibitory efficacy across diverse malignancies, including multiple myeloma (RPMI-8226, U266) and breast cancer (4T1), which suppresses VEGF expression to potently ameliorate tumor neoangiogenesis (Xue et al., 2012

Methods 17 , 399404 (2020)

Low-molecular-weight thiol transferases in redox regulation and antioxidant defence

All references to benefits describe laboratory measurements only

Thrombus Assessment Following sacrifice, the superior sagittal sinus and peripherally the portal vein, external jugular vein, inferior caval vein, superior mesenteric vein, hepatic vein, superior mesenteric artery, hepatic artery, and abdominal aorta were removed from the rats, and the clots were weighed (Vukojevic et al., 2018

J Clin Invest (2013) 123:437589