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A recent study demonstrated the ability of a dendrimer-conjugated NAC (D-NAC) to specifically target glial and astrocyte cells, indicating potential to alter GSH levels in specific cell populations without altering levels throughout the CNS (Nance et al., 2017

Any increases in iron uptake or reduced capacity for iron storage contributes to iron overload and the potential to generate highly reactive hydroxyl radicals through the Fenton reaction

One of these approaches is to locally open the BBB for a certain time, using an adjustable RF field to achieve hyperthermia with commercially available IONPs injected through the medial cerebral artery (Fig

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These findings underscore the potential of SelP as a biomarker for disease severity and its pivotal role in the pathogenesis of various malignancies (118, 197200)

AT, aquatic training + placebo