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Proteolytic digestions of Mpro revealed Cys300 as a primary target of glutathionylation, and experiments using a C300S Mpro mutant revealed that Cys300 is required for inhibition of activity upon Mpro glutathionylation

Here we describe a study designed to characterise conjugates that form between heme and glutathione

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Encapsulated in liposomes, this formulation enhances absorption, supporting cellular detoxification and protecting against oxidative stress

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Such a novel strategy would impact the majority of chronic diseases contributing to the bulk of morbidity and mortality in the Western world, and, thus, even minor benefits across many conditions may substantially impact population-wide health and longevity.