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More recently, the same authors carried out a further RCT on 80 CFS patients, showing that CoQ 10 + NADH supplementation was well tolerated and safe and reduced maximum heart rate significantly at week 8 versus baseline during a cycle ergometer test, supposing that at the basis of this there was an improvement of the endothelial function

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Differential activities of the ubiquitin-proteasome system in neurons versus glia may account for the preferential accumulation of misfolded proteins in neurons