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Whereas non-cystic fibrosis cells upregulate CHAC1 following infection with various pathogens (including Pseudomonas aeruginosa , human coronavirus, cytomegalovirus, tick-borne flaviviruses, Zika virus, and Mycoplasma hominis ), cystic fibrosis cells show an impaired response

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Using a similar strategy, exocyclic enones displaying antitumor activity were produced by a GSH-dependent reaction catalyzed by GST (Hamilton et al., 2002, 2003)