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An interesting next phase is to try to understand how we get these benefits, because maybe there are ways to further exploit that benefit for even better long-term improvements in graft and patient survival. Severe adverse events were rare, according to the researchers

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While mild nausea and early satiety are expected and generally manageable, patients should seek immediate medical attention for severe or persistent vomiting, severe abdominal pain (especially if radiating to the back), right upper quadrant pain with fever or jaundice, or inability to maintain adequate hydration

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However, there is currently no direct evidence confirming the neuropsychiatric effects of GLP1RA in humans, and high-quality randomized controlled trials (RCTs) are still lacking