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Thank you Your baseline risk was likely higher than average due to the mutation but the surgery was a definite risk factor as well likely a combination of the two

A conceptual summary of the multi-level consequences of heat stress is presented in Figure 1 , illustrating how elevated environmental temperatures initiate a cascade of disruptions from whole-animal health and pathogen dynamics to immune function and cellular responses

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Of the 34 patients enrolled, two withdrew before the start of treatment

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J Biol Chem 291(44):2286122867 Zhang C, Liu J, Zhao Y et al (2016b) Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis