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While numerous genes participate in antioxidant defense, only a few selected ones possess the capacity to influence the human response to environmental factors that induce oxidative stress

Microglia and astrocytes in brain homeostasis and pathology Microglia are the immune cells residing in the brain and spinal cord, monitoring infection and causing stress responses

[11] This information is protected by DNA repair mechanisms and propagated through DNA replication

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CREB, cAMP-response element binding protein

Funding Statement This work was supported by Fundao para a Cincia e a TecnologiaFCT to IBIMED (UIDP/04501/2020 and UIDB/04501/2020) and LAQV/REQUIMTE (UIDB/50006/2020)