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Ipamorelin is made up of five amino acids forming a pentapeptide, and works as a selective agonist targeting the ghrelin or growth hormone secretagogue receptor (GHS-R)
Preclinical studies have shown that inhibiting mitophagy or restoring MPC function can effectively suppress tumor cell viability and synergize with conventional chemotherapeutics such as 5-FU and oxaliplatin [48, 50]
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10.1146/annurev.pa.25.040185.003435 3
2014;53:e557
doi: 10.3168/jds.2013-7625 65 CouperKNBlountDGRileyEM
