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Species-Specific Thiol-Disulfide Equilibrium Constants: A Tool to Characterize Redox Transitions of Biological Importance

In 200 l of whole blood, erythrocytes were lysed with ammonium-chloride-potassium solution, and then leukocytes were resuspended in phosphate saline solution

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Some drugs are so extensively metabolized on the first pass that they are not effective when given orally and must be administered by an alternative route that bypasses the liver (e.g., sublingual nitroglycerin, IV lidocaine)

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