anti-inflammatory activity curcumin reseratrol flavonoids glutathione Frontiers Curcumin, resveratrol, and other polyphenols

Clinical trials showed an average loss of 6 pounds over 12 weeks compared to 2 pounds with placebo

Ghosh B

[DOI] [PubMed] [Google Scholar] 133.Huang W, Booth DM, Cane MC, Chvanov M, Javed MA, Elliott VL, Armstrong JA, Dingsdale H, Cash N, Li Y, Greenhalf W, Mukherjee R, Kaphalia BS, Jaffar M, Petersen OH, Tepikin AV., Sutton R, Criddle DN

Vitamin B12 injections are generally considered safe when administered by a trained healthcare professional following a suitability assessment

( A and B ) Weight gain of PAR2-G37I, PAR2-R38E, and WT male ( n = 19/16/13) ( A ) and female ( n = 7/7/7) ( B ) mice on HFD

However, both compounds individually cause: Nausea (60-80% of users at higher doses) Vomiting (20-35%) Diarrhea (25-40%) Injection site reactions (15-25%) Potential pancreatitis (rare but serious) Combining these compounds could theoretically amplify these effects, though the actual incidence and severity remain unstudied