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Adv Exp Med Biol (2018) 1063:1332

Neuromodulatory effect of curcumin on catecholamine systems and inflammatory cytokines in ovariectomized female rats

The lack of awareness (60), paucity of diagnostic tools (60), heterogeneity between patients (26, 60, 529), disbelief from health care workers (60), unpredictable relapses, and multiplicity of symptoms have made it difficult to formulate a treatment for ME/CFS

2b) as well as a decrease of the apparent catalytic efficiencies (Fig