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Glutamic acid is the most abundant amino acid in the diet, and a high level of free glutamate in some foods results in an umami taste (e.g., tomatoes, mushrooms, cheeses) ( TDR4 -silenced and control tomato fruit, and four of these were upregulated, including glutamate dehydrogenase ( GDH1 ) (1.11-fold), glutamine synthetase ( GS ) (6.04-fold), glutamate decarboxylase 1 ( GAD3 ) (2.20-fold), and a gene encoding isocitrate dehydrogenase (1.99-fold) (Supplementary Table S2)

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