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The only controlled study in trained athletes ( Mechanistic implications for endurance athletes Inhibiting mitochondrial fatty-acid uptake acutely forces a greater reliance on glucose and glycogen during exercise

One such approach involves the use of mitochondrially targeted zinc finger nucleases (mtZFN), a heterodimer nuclease consisting of a DNA binding site (tandem repeat of zinc fingers binding three bases each), and a DNA cleavage domain (a Fok1 endonuclease)

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Glasgow, L., Owen, G., May-Hardford, J., Antoine, S., Forde, M., Perez, E., Indar, L

Cheatham CL, Nieman DC, Neilson AP, Lila MA

128 Meanwhile, SLC1A5 expression was also regulated by STAT3 in AML cells
