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doi: 10.1096/fasebj.2018.32.1_supplement.538.4

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Exogenous MG exposure (Figure 4) further revealed two distinct ferroptosis-promoting mechanisms: covalent binding-mediated glutathione depletion, which crippled glutathione peroxidase activity, and suppression of selenoprotein biosynthesis, evidenced by diminished GPX4 and SLC7A11 expression (Figure 5)

S.McLaughlinR.AdamsJ

I have drawn a circle around the mark to see if it is increasing in size, it has been increasing each day