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In this review, we have discussed the numerous sources that generate several type of free radical/non- radical species such as superoxide and nitric oxide, singlet oxygen, nitroxyl anion, nitrosyl cation, hypochlorous acid, etc

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Herein, we have developed a novel redox-sensitive pegylated phospholipid, termed as DOPE-SS-PEG, which can form a glutathione (GSH)-triggered precision explosive system (GPS) for simultaneously improving circulation stability, tumor specificity, and chemosensitivity, leading to explosive anticancer effects