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Recently, the protective effect of EZH2 inhibition has been demonstrated, and various EZH2 inhibitors have been approved for clinical cancer treatments [32]

Proc Natl Acad Sci U S A 112, E22172224

79 As mentioned above, epigenetic alterations take place when methyl groups are added to or removed from a cytosine base (C) of DNA or when modifications are made to proteins called histones that bind to the DNA in chromosomes

527 Currently, the drug is in Phase II clinical recruitment to compare the safety and efficacy of three different doses in patients with nAMD (NCT05637255)

Burbacher, T

and decision to submit the manuscript for publication
