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[DOI] [PMC free article] [PubMed] [Google Scholar] 428.Cherian JJ, Parvizi J, Bramlet D, Lee KH, Romness DW, Mont MA
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35 The nerve fibers innervating the painful degenerated IVDs are primarily small unmyelinated neurons expressing the neural growth associated protein (GAP)43 and coexpress the neuropeptide substance P (SP) that confirm their nociceptive identity

Research shows protective effects on lean tissue

long-term effects on NAD+ metabolism, liver function, and cardiovascular health are unknown

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