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Rats were deeply anesthetized with sodium pentobarbital and transcardially perfused with 0.1 m PBS followed by 4% paraformaldehyde in 0.01 m PBS for 30 min

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The concern about a disulfiram-like reaction that is sometimes cited for nitrofurantoin is a myth: that reaction is caused by metronidazole and certain other antibiotics that inhibit aldehyde dehydrogenase