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(2014) Meta-analysis of methylcobalamin alone and in combination with prostaglandin E1 in the treatment of diabetic peripheral neuropathy

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[DOI] [PubMed] [Google Scholar] 210.Dobrzyn A, Ntambi JM

Peripheral neuropathy, subacute combined degeneration of the spinal cord, or cognitive impairment indicate more advanced deficiency and generally require intensive treatment over extended periods

Fraser et al, however, reported no resistance by patients to reducing the frequency of their injections