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and independent third-party laboratories corroborate in-house analytics to maintain traceable quality metrics appropriate for research use

doi: 10.3904/kjim.2016.334

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Stojanovic et al., 2016)

A study by Yang et al (117), using a rat acute myocardial infarction model and in vitro CF experiments, demonstrated that medium-to-high doses of TSA notably improved left ventricular function, reduced collagen deposition and downregulated TGF-1, Col1a1, Col3a1 and -SMA expression while upregulating miR-29b (117)

Furthermore, this damage causes a mutation in the DNA molecules regardless of their location, which eventually causes defects in the translated proteins and ultimately impacts multiple facets of cellular physiology [121]