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Cancer cells tagged by calreticulin on their surface stimulate an immunogenic cancer cell death by enabling their phagocytosis by the dendritic cells of the immune system which in turn triggers T-cell-mediated immune response 27,28,29

The normalized TR-FRET signals were plotted against the compound concentrations on a logarithmic scale

doi:10.1016/0003-2697(88)90564-7

First-in-human clinical trials present significant challenges, especially concerning participants safety

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Laing, A