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However, maintaining a large terminal field would probably impose a significant metabolic and proteostatic burden on the cell body

Furthermore, tau aggregation can impair mitochondrial dynamics, leading to decreased mitochondrial motility and compromised mitochondrial function

delivered RNAliposomes (RNALPX) encoding four TAAs (New York oesophageal squamous cell carcinoma 1, melanoma-associated antigen A3, tyrosinase, and transmembrane phosphatase with tensin homology) into dendritic cells as a cancer vaccine [247]

[DOI] [PubMed] [Google Scholar] 87.Dunnill C., Patton T., Brennan J., Barrett J., Dryden M., Cooke J., Leaper D., Georgopoulos N.T

Similarly, losing a lot of weight or becoming underweight (BMI less than 20) can delay periods as well, particularly in the context of any disordered eating

Metformin inhibits melanogenesis by reducing intracellular cyclic adenosine monophosphate (cAMP) accumulation, but its low lipophilicity obligates its use in high concentrations for topical efficacy [62]