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The four target lesions included an abdominal mass (abdominal mass #1), a representative hepatic parenchymal lesion (hepatic lesion #1), and cortical masses in the left and right kidneys (left renal lesion #1 and right renal lesion #1)

Contraindications Severe Renal Impairment Hypersensitivity leucopenia, neutropenia or thrombocytopenia Severe reactions to fluoropyrimidine therapy Complete DPD deficiency Pregnant or breast-feeding Side Effects Abdominal pain, Rash, dry or itchy skin, Tiredness, loss of appetite (anorexia), Diarrhea, Vomiting, Nausea, Stomatitis, Hand-and-foot skin-reaction, Fever, Infection, Chest pain, Steven-Johnson syndrome Pregnancy & Lactation Pregnancy category D

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The Jarisch-Herxheimer reaction in leptospirosis: a systematic review

Tetrahydrocurcumin downregulates MAPKs/cPLA2 Signaling and attenuates platelet thromboxane A2 generation, granule secretion, and Thrombus growth