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The central beneficial action of mexidol may be mediated by ion channels containing glutamate- and GABA-ergic components, predominantly via suppression of ion currents via the NMDA receptor complex (Motin et al., 2012)

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Indeed, a recent study from Palmisano et al., 2012

Furthermore, nitric oxide is a potent vasodilatorit causes blood vessels to widen and relax

Combination therapies that exploit the synergistic effects of PMs and other compounds, such as natural polyphenols (e.g., curcumin), antimicrobial peptides (e.g., microbisporicin), efflux pump inhibitors, and other secondary metabolites (e.g., netropsin or FA) are drawing increasing attention