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NAC, an antioxidant and a precursor for GSH, has been used in clinic to improve motor and mental abilities of PD patients, possibly by restoring dopaminergic neuron functions [158, 159]

Polyphenolic antioxidants in lipid emulsions: partitioning effects and interfacial phenomena

Notch signaling is also considered a key player in carcinogenesis, acting as either an oncogene or a tumor suppressor in various malignancies, including different TC histotypes, thus suggesting that its apparent dual role is cell type and context-dependent [152,153]

PLoS ONE 8 , (2013)

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