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In the case of redox stress, two molecules of GSH reduce one molecule of hydrogen peroxide in the presence of glutathione peroxidases, generating one molecule of glutathione disulfide (GSSG), an oxidized form of GSH, and two molecules of water 122 , 123
An organism that can simply sequester its vitamins from the environment may therefore be at an evolutionary advantage, as the process of endogenous enzymatic de novo synthesis of these compounds would have entailed a disadvantageous cost in terms of energy expenditure, the need for cellular machinery, and the oxidative stress involved in metabolism [3,4]
Glutathione acts as a natural shield against UV-induced oxidative stress, preserving the hairs strength and colour
Interestingly, the vast majority of 5-HT is produced by intestinal EC cells
