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doi: 10.3389/fphar.2025.1598978 Received 24 March 2025 Accepted 03 June 2025 Published 20 June 2025 Volume 16 - 2025 Edited by Adolfo Andrade-Cetto, National Autonomous University of Mexico, Mexico Reviewed by Kulbhushan Thakur, University of Delhi, India Bizhar Ahmed Tayeb, University of Szeged, Hungary Updates Copyright 2025 Shen, Yu and Wang

The Mass Spectrometry Laboratory at the Karolinska Institute 19441987

A redox shift is a change in the bioenergetic supply of electrons, leading to changes in the intracellular ratio of NAD + /NADH as redox currency, oxidized glutathione over GSH (GSSG/GSH) as redox buffer, and plasma cystine/cysteine (cySS/cys) as systemic buffer

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A 2013 survey suggested that intranasal GSH is well tolerated