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Carnitine also significantly increases dopamine levels in the cortex, hippocampus, and striatum of the rat brain [51]

The misfolding and aggregation of Syn into amyloid fibrils is a pathogenic hallmark of several neurodegenerative diseases called synucleinopathies, such as Parkinsons disease

Using marker substrates to identify induction of specific P450s, Kreuger and coworkers provided a summary of sex and species differences in the magnitude of CYP enzyme induction

Nestes casos, podem existir particularidades no metabolismo e na eliminao dos seus derivados que afetem a capacidade de metabolizar a L-carnitina de forma eficiente, o que poderia agravar a sua condio

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