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In a 2020 study published, there were no adverse effects in single-dose studies

First-line nivolumab plus ipilimumab with chemotherapy versus chemotherapy alone for metastatic NSCLC in CheckMate 9LA: 3-year clinical update and outcomes in patients with brain metastases or select somatic mutations

Milbank Quarterly , 82(2): 257-282

The right protocol depends on factors like your baseline metabolic health, body composition, and other therapies you might be using

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