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Published research has demonstrated that GHK-Cu can influence numerous genes involved in: extracellular matrix synthesis collagen turnover tissue remodelling inflammatory signalling antioxidant defence stem-cell related pathways angiogenesis Copper binding is essential to this biological activity, allowing GHK-Cu to participate in cellular signalling processes associated with tissue maintenance and repair

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[DOI] [PMC free article] [PubMed] [Google Scholar] 237.Lindner M, Trebst C, Heine S, Skripuletz T, Koutsoudaki PN, Stangel M

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