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A significantly worse diastolic dysfunction was observed in the study group, with higher median values of peak E/e (10.9 [9.4, 13.8] vs 7.4 [5.9, 10.5], p 0.043)

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Diagnostic lab work was notable for a thyroid panel consistent with thyrotoxicosis--TSH level 0.005 uIU/mL, free thyroxine level of 6 ng/dL, and free triiodothyronine level of 1218 pg/dL)

Treated patients were propensity score matched to the external controls from the PRO-ACT database

The solved X-ray crystal structure of tetrameric MSA-DH reveals the key catalytic residues Cys 290 and Glu 256 , accessible through opposing substrate and cofactor funnels

The DiGeorge syndrome , also called velocardiofacial or 22q11.2 deletion syndrome (22q11.2DS), is caused by a hemizygous microdeletion (1.53 Mb) on chromosome 22 DiGeorge syndrome The prevalence rate of this condition is ~1 in 4000 [356]