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Description
ACE2 knockout mice are more susceptible to high-fat diet-induced pancreatic beta-cell dysfunction than wild-type mice (79)

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C.JacobsonR

The synthesis of pyruvate occurs nearly exclusively in the cytosol and its oxidation occurs exclusively in the mitochondria, therefore transport into the mitochondria is critical for overall pyruvate homeostasis

Neurology, 86(16 Supplement), P3-154
