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The safety profile was statistically indistinguishable from placebo across all trials

406 Therefore, endogenous GLP-1R signaling in astrocytes plays a critical role in maintaining mitochondrial homeostasis and is dependent on FGF21 to effectively regulate glucose metabolism

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S.SeiwerthS.RogicD.KusecV.et al (2004)

In preclinical work, BPC-157 has been evaluated in cell-based and animal models, in which investigators examine tissue integrity, barrier function, and responses to experimentally induced stress or injury under controlled conditions