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Primary Metabolic Pathways Beta-3-Adrenergic Receptor Modulation Research in obese mice demonstrated that AOD-9604 increases expression of beta-3-adrenergic receptor RNA in adipose tissue, upregulating levels from those seen in obese animals to levels comparable with lean controls

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In laboratory investigations, researchers found that NNMT overexpression correlates with obesity and metabolic dysfunction, while its inhibition produces remarkable metabolic benefits

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