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Description
Preserved lean muscle mass while reducing fat mass Studies showed that NNMT inhibition selectively reduced adipose tissue without negative effects on skeletal muscle mass, suggesting a favorable body composition profile
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PMID 11713213
In fact, SIRT1 and CD38 have several similarities in their enzymatic and catalytical properties [71], and CD38 has been proposed as a model enzyme for the study of the mechanism of SIRT1 catalysis [71]
