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Can acute otitis media be prevented

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Glucose-6-phosphate dehydrogenase (G6PD) in the pentose phosphate pathway is the dominant enzyme that produces the required amount of NADPH during the conversion of glucose-6-phosphate to D-glucono-1,5-lactone-6-phosphate [63]

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Specifically, AMs are prone to be polarized into immunosuppressive M2 phenotype in pulmonary metastasis, while immune-promoting M1 phenotype is effective in immunotherapy

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