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Observational studies A large number of cross-sectional and prospective cohort studies have associated elevated blood homocysteine concentrations with measures of poor cognitive scores and increased risk of dementia, including Alzheimer's disease (reviewed in 67, 69)

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Researchers interested in understanding the broader context of GLP-1 receptor agonist research can explore how tirzepatide compares to other compounds in this class through our semaglutide versus tirzepatide comparison , the mazdutide comparison , and our overview of peptides for weight loss more broadly