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As a main microvascular complication, diabetic kidney disease (DKD) is a serious life-threatening condition that is characterized by persistent albuminuria and progressive decline in renal function or lead to end stage renal disease [3]

, Selective osteoblast overexpression of IGF-I in mice prevents low protein-induced deterioration of bone strength and material level properties

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Indeed, inhibition of CBS can yield overall higher H 2 S production through CSE, which presents a higher catalytic efficiency

10.2337/db11-0571 244 NathanD

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