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Yang et al developed a carrier-free nanoregulator (NanoDS) through the self-assembly of donepezil and simvastatin for direct nose-to-brain delivery

Another important category is addition reactions, where a nucleophile adds to an electrophilic double bond

Next, a metabolome analysis based on CETOFMS was performed, and 400 metabolites were detected in the three culture groups

In the brain, a bidirectional relationship between iron overload and neuroinflammation creates a vicious cycle that could eventually boil down to ferroptosis-mediated neuronal death

Schematic diagram showing protein methylation on arginine residues