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These interventions encompass antidepressants, monoamine reuptake inhibitors, serotonin, and dopamine receptor antagonists, gabapentinoids, and cannabinoids, as well as others [204]

"These results reinforce our confidence in CagriSema, and we continue to study the potential of this combination through the REDEFINE trials." CagriSema is an investigational product that combines the GLP-1 RA, semaglutide, with an amylin analogue, cagrilintide

Nicotine affects the functional activity of ion transporters, including Na + , K + , 2Cl cotransporter and Na + , K + -ATPase on BECs and inhibits P-gp activity in the CNS (Paulson et al., 2006

Bloodwork and lab panels to establish baseline biomarkers (hormone levels, metabolic profile, liver/kidney function, etc.)

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