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Lpez-ErauskinJFourcadeSGalinoJRuizMSchlterANaudiAet alAntioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy

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Under this perspective, as reported in a systematic analysis for the Global Burden of Disease Study 2021 [1, 2], the age-standardized rates of deaths per 100,000 individuals attributed to 37 unique conditions affecting the nervous system that now include neurodevelopmental disorders, late-life neurodegeneration, and emergent conditions such as cognitive impairment following coronavirus disease 2019 (COVID-19), has decreased by 33.6% from 1990 to 2021

It has been hypothesized that the somnogenic effects of GSSG are due to its ability to attenuate glutamatergic neurotransmission in the brain and stimulate nitric oxide synthase or general oxidative stress signaling mechanisms [19,20]

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Da diese Wirkungen direkt mit der Geschwindigkeit biologischer Alterung zusammenhngen, betrachten wir Glutathion als messbaren Einflussfaktor auf das biologische Alter und nicht als alleinige Wunderbehandlung