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AsianAustralas J Anim Sci 26(8):11891196 Justus J, Weigand EA (2014) Moderate zinc deficiency does not impair gene expression of PPAR, PPAR, and mitochondrial enoyl-CoA delta isomerase in the liver of growing rats

In actual fact, Alejandra Snchez-Muoz and others showed that a leaf extract of this plant improved mitochondrial respiration, while increasing levels of intracellular antioxidants like GSH, glutathione reductase and HO-1 activity, to reduce excess production of ROS liver cells of STZ-induced diabetic rats (Teodoro et al., 2018)

10.1159/000446586 36 PinelesS

KIM-1, kidney injury molecule-1

While antioxidants like vitamin C or glutathione reduce oxidative damage, aging involves multiple factorsgenetics, inflammation, and telomere shorteningbeyond ROS alone

A double-edged sword: the anti-cancer effects of emodin by inhibiting the redox-protective protein MTH1 and augmenting ROS in NSCLC
