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Preclinical evidence shows the significance of microbial metabolites and immune signaling in driving these effects, and recent clinical studies further supports these findings (Touchefeu et al., 2014

doi: 10.1042/bj3220213

Thisse C, Degrave A, Kryukov GV, Gladyshev VN, Obrecht-Pflumio S, Krol A, Thisse B, Lescure A

In the future, the cost-effective small-molecules with specific PCSK9 inhibitory ability may reduce the manufacturing costs and promote the usage of PCSK9i for primary prevention of ASCVD

Quality of life prediction in children with joint hypermobility syndrome

Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription