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Understanding the dualistic nature of ferroptosis will be vital for designing safe and effective interventions

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The causal role of dysbiosis has been confirmed by fecal microbiota transplantation from MNPs-exposed mice into germ-free recipients, which replicates metabolic disruptions including weight gain and lipid dysregulation [85]

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Aggrecan-binding peptide Aggrecan, an abundant ECM molecule in cartilages, is characterized by a high fixed charge density attributed to numerous chondroitin and keratan sulfate moieties