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Indication Carence en vitamine B12 Anmie pernicieuse Neuropathie secondaire Utilisation Adultes En injectio Dose de charge: 1 ampoule par jour ou 3 ampoules par semaine rpter en fonction des rsultats hmatologiques Dose d'entretien: 1 ampoule par mois Par voie oral Dose de charge: 1 ampoule par jour pendant 15 jours 1 mois Dose d'entretien: 1 ampoule tous les 10 jours En injectio Dose de charge: 1 ampoule par jour jusqu' amlioration des symptmes cliniques Dose d'entretien: 1 ampoule par mois 200mcg 1000 mcg mois ou tous les 2 mois Mode d'administration Solution injectable et buvable pour administration par voie sous-cutane, intramusculaire, intraveineuse ou orale

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Following a 2014 study (published in JAMA Psychiatry) that found children born to mothers who used acetaminophen during pregnancy had a much higher risk for developmental disorders, a Johnson & Johnson scientist complimented the strength of this studys design and the strength and robustness of the association (acetaminophen to autism)

The results showed that treatment with phyllanthin nanoparticles resulted in decreased ALT and AST levels, repair of cell membrane damage from CCL4, and improvement in liver fibrosis

doi: 10.1016/j.ijantimicag.2012.10.009 470 YuQ.DingX.ZhangB.XuN.JiaC.MaoJ.et al

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