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10.1016/j.cell.2011.02.034 52 ElifaniF.CrispiS.FilosaS.CastaldoS.CapocciL.MadonnaM.et al (2016)

et al., 2020).Chronic hepatitis B is an infectious disease caused by the hepatitis B virus and represents one of the major global causes of cirrhosis and hepatocellular carcinoma (van Rossum et al., 2001

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This involves not only targeting specific pathways to enhance CD8 + T-cell infiltration and intervene in their spatial distribution but also counteracting the cell intrinsic functional impairments that suppress T cells within the TME

Funding This study was supported by the National Natural Science Foundation of China (grant numbers 32170468 and 31872198)

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