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International Journal of Cosmetic Science 30(2):87-95. [doi.org]

Severe hypotension, which may require cardiovascular support

She was treated with high-dose intramuscular vitamin B12 (2,000 g/day), resulting in rapid clinical and hematologic improvement

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Participants 283 patients 65 years with VB12 deficiency were randomly assigned to oral (n=140) or IM (n=143) treatment arm

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